Early goal-directed therapy: a UK perspective.
نویسندگان
چکیده
The surviving sepsis campaign developed guidelines in 2003 that were designed to increase physician awareness of sepsis and to develop a series of recommendations for the management of the patient with sepsis. The guidelines had the support of 11 international professional organisations across a variety of specialties, and advocate aggressive, early goal-oriented resuscitation in appropriate patients.
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Severe sepsis and septic shock is a life-threatening disease. It is combined with multi-organ failure. In the past decade, early goal directed therapy has been proposed as an effective treatment strategy for better outcome. Recent epidemiologic studies showed that the outcome of sepsis has been improved with the introduction of early goal directed therapy. However, it is unclear which elements ...
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BACKGROUND Early goal-directed therapy has been endorsed in the guidelines of the Surviving Sepsis Campaign as a key strategy among patients presenting with severe sepsis or septic shock. But more importantly, early goal-directed therapy also became standard care for non-septic critically ill patients and was adopted for high-risk surgical patients. DISCUSSION Importantly, transfusion of red ...
متن کاملImpact of time to antibiotics on survival in patients with severe sepsis or septic shock in whom early goal-directed therapy was initiated in the emergency department.
OBJECTIVE To study the association between time to antibiotic administration and survival in patients with severe sepsis or septic shock in whom early goal-directed therapy was initiated in the emergency department. DESIGN Single-center cohort study. SETTING The emergency department of an academic tertiary care center from 2005 through 2006. PATIENTS Two hundred sixty-one patients undergo...
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ورودعنوان ژورنال:
- Emergency medicine journal : EMJ
دوره 23 11 شماره
صفحات -
تاریخ انتشار 2006